10 One Chicago Exits That Left Fans Heartbroken (And Still Not Over It)

The One Chicago universe has experienced many significant losses across all series, but some have been more devastating than others. Heading into the 2025–2026 network TV season, NBC’s popular franchise (which includes Chicago FireChicago PDChicago Med, and Chicago Justicehas produced 36 seasons and almost 730 episodes, and it’s showing no signs of stopping. With more seasons and episodes on the way, there are sure to be many more heartbreaking departures, given the nature of the three current shows.

The One Chicago franchise features characters running into burning buildings, chasing down dangerous criminals, and treating patients in the emergency department of one of the city’s biggest hospitals. So, while some jobs are more perilous than others (looking at you, Chicago Fire), death is all around the characters. They lose people almost every season. Of course, some characters leave the One Chicago universe in one piece, but that doesn’t make their exits hurt any less. No matter how they leave, significant characters departing their respective series will always be upsetting.

10Leslie Shay

Played By Lauren German

Leslie Shay’s tragic death in Chicago Fire season 3 was the One Chicago franchise’s first major loss, and it still stings to this day. During the season 2 finale, almost the entire Firehouse 51 crew (sans Chief Boden) entered a building that seemingly only had a small fire inside. However, an explosion wracked the structure, leaving the audience wondering the fates of several characters. Unfortunately, they had to wait a few months until the season 3 premiere, which revealed that Shay had died in the explosion.

Stella Kidd and Kelly Severide learn shocking news during the Chicago Fire season 13 finale, and the development saves their latest story.